Last edited by Tern
Saturday, October 10, 2020 | History

4 edition of Mitosenes and Related Antitumor Drugs found in the catalog.

Mitosenes and Related Antitumor Drugs

Rational Design of Cytostatic Agents (Medical intelligence unit)

by Marc Maliepaard

  • 141 Want to read
  • 12 Currently reading

Published by R G Landes Co .
Written in English

    Subjects:
  • Derivatives,
  • Mitomycin C,
  • Structure-activity relationships,
  • Health/Fitness

  • The Physical Object
    FormatHardcover
    ID Numbers
    Open LibraryOL12198632M
    ISBN 101570593353
    ISBN 109781570593352
    OCLC/WorldCa34116393

    Osmium Complexes with Azole Heterocycles as Potential Antitumor Drugs Osmium Complexes with Azole Heterocycles as Potential Antitumor Drugs Antitumor Drug – Anticancer Drug. In: Kretsinger R.H., Uversky V.N., Permyakov E.A. (eds) Encyclopedia of Metalloproteins. Search within book. Type for suggestions. Table of contents Previous. Page 5. Anticancer drug, any drug that is effective in the treatment of malignant, or cancerous, disease. There are several major classes of anticancer drugs; these include alkylating agents, antimetabolites, natural products, and hormones. In addition, there are a number of drugs that do not fall within.

    Treatment of adult T‐cell leukemia/lymphoma with MST‐16, a new oral antitumor drug and a derivative of bis(2,6‐dioxopiperazine) Ryuzo Ohno M.D. Corresponding AuthorCited by: Photodynamic therapy (PDT) is a light activated modality that works well for many diseases, particularly antitumor treatment. A photosensitizer is a great determinant of the PDT outcome. Nowadays significant efforts have been focused on developing a new photosensitizer. In the current study, we present a nov.

      Mitosenes without good leaving groups were found to be stable upon reduction. In the presence of acetoxy groups at C-1 and C, the C site is the most reactive site upon reductive activation. This is opposite to the case of mitomycin C, where the C-1 Cited by: “Drs. Butterfield, Kaufman and Marincola on behalf of the SITC have created a comprehensive must-have resource covering the basic and translational science behind approved and investigational immune therapies, and disease-by-disease clinical application of the therapies, written by leaders in the field. The textbook will be highly valuable reading for those just entering the field and for.


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Mitosenes and Related Antitumor Drugs by Marc Maliepaard Download PDF EPUB FB2

This monograph discusses the development of mitosenes and related antitumour drugs. Mitosenes are derived from the clinically used cytostatic agent mitomycin C, the prototype of a bioreductive alkylating agent.

Author(s): Maliepaard,Marc, Title(s): Mitosenes and related antitumor drugs: Mitosenes and Related Antitumor Drugs book design of cytostatic agents/ Marc Maliepaard.

Country of Publication. Chemotherapy is a category of cancer treatment that uses chemical substances, especially one or more antitumor drugs that are given as part of a standardized chemotherapy regimen. Chemotherapy may be given with a curative intent which almost always involves combinations of antitumor drugs, or it may aim to prolong life or to reduce : He Wang, Xiaoyong Li, Pei-Hsin Cheng, Maria Luisa Bondì, Bi-Yun Wang, Ymera Pignochino.

Antitumor chemotherapy is nowadays a very active field of research, and a huge amount of information on the topic is generated every year. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book addresses the need for an updated treatment from the point of view of medicinal chemistry and drug design.

The mitosenes are a class of organic chemicals based on a quinone-containing three-ring structure related to the two-ring core of the indolequinones. They are derived from the mitomycins by reduction and are the active alkylating agents responsible for the antitumor activity of the mitomycins.

Title: Mitocans: Mitochondrial Targeted Anti-Cancer Drugs as Improved Therapies and Related Patent Documents VOLUME: 1 ISSUE: 3 Author(s):Stephen J. Ralph, Pauline Low, Langfeng Dong, Alfons Lawen and Jiri Neuzil Affiliation:Genomic Research Centre, School of Medical Science, Griffith University, 58 Parklands Drive, Southport, Queensland,Australia.

Purchase Cancer Immunotherapy - 2nd Edition. Print Book & E-Book. ISBNFrom todrugs were approved as antitumor agents; 30% of these were obtained from natural sources, 57% were natural agents with semisynthetic modifications and 34% had natural product mimetic pharmacophores [13].

Although targeted therapies, such as monoclonal antibodies, have greatly improved. the 30th of September for all approved antitumor drugs worldwide. As in earlier reviews, only the first approval of any drug a chapter on biodiversity and drug discovery (in a Brazilian book);17 a review on marine-derived warheads for “small” meaning less than compounds in a related library) are given in four recent Author: David J.

Newman, Gordon M. Cragg. Medications and prescription drug information for consumers and medical health professionals. Online database of the most popular drugs and their side effects, interactions, and use. The Drug Book: From Arsenic to Xanax, Milestones in the History of Drugs (Sterling Milestones) [Gerald, Michael C.] on *FREE* shipping on qualifying offers.

The Drug Book: From Arsenic to Xanax, Milestones in the History of Drugs (Sterling Milestones)Cited by: 3. Use the A to Z list below to find consumer-friendly information about drugs for cancer and conditions related to cancer. The list is in alphabetical order by generic name and brand name.

You can also find this information on our pages organized by cancer type and cancer-related condition: This page lists and links to NCI's pages of drugs. Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents.

Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen. Chemotherapy may be given with a curative intent (which almost always involves combinations of drugs), Other names: chemo.

Among these compounds, mitomycin C is know to be an effective antitumor antibiotic. Other closely related antibiotics, mitomycin A (MMA), mitomycin B (MMB), mitomycin D (MMD), mitomycin F (MMF) and porphiromycin (PFM), have been subsequently isolated (Kasai and Kono, ).Cited by: Mitomycin Antitumor Compounds.

Interaction of Transition Metal Ions with Mitomycin C. Solution Structure and Biological Activity of a Pd2+−MMC Complex. Journal of Medicinal Chemistry46 (9), DOI: /jm Marcy Hernick and, Richard F.

Borch. ANTITUMOR+DRUGS - Free download as Powerpoint Presentation .ppt), PDF File .pdf), Text File .txt) or view presentation slides online. Scribd is the world's largest social reading and publishing site.

Chemical Synthesis of Nucleoside Analogues covers all the major classes of nucleosides, including pronucleotides, C-nucleosides, carbanucleosides, and PNA monomers which have shown great promise as starting points for the synthesis of nucleoside analogues.

The book also includes experimental procedures for key reactions related to the synthesis. The in vitro activity of this series of mitosenes in an A and a L cell line demonstrated a clear bilinear dependence on log P with optimal activity at log P values of and respectively.

These antitumor antibiotics have played an important role in the development of antitumor agents. Structure-activity relationship of a novel antitumor ansamycin antibiotic trienomycin A and related compounds.

Journal of III. Potentiation of antitumor drugs and its mechanism of action. Journal of Antibiotics (Tokyo) –. Start studying Antitumor drugs.

Learn vocabulary, terms, and more with flashcards, games, and other study tools.Antitumor antibiotics: These drugs bind with DNA and prevent the synthesis of ribonucleic acid (RNA), which is imperative for cell survival.

Antitumor antibiotics are used to treat many different cancers. Some of the drugs in use are dactinomycin, daunorubicin, doxorubicin, epirubicin, idarubicin, and mitoxantrone.The book also contains a section containing most interesting methods for synthesis and modification of heterocycles developed by the workers from CIS and Baltic countries of the former Soviet Union in several past years.

New opportunities for synthesis of mitosenes, mitomycins, and antitumor drug EO-9 Buzykin B.I., Eliseenkova R.M.